Medication for management of pregnancy-induced hypertension

Hypertension refers to increased arterial blood pressure and can be divided into two categories: primary and secondary. Primary hypertension caused by angiogenic degenerative changes is a degenerative disease. With liberalization of China’s reproduction policy and increases in maternal age, the prevalence of pregnancy-induced hypertension (PIH) in China has increased gradually. PIH is not a type of primary hypertension, but there are differences in the treatment of these two types of hypertension. Here, we review the choice and use of drugs for PIH management using drugs for the management of primary hypertension as a reference. First-line drugs such as labetalol, nifedipine, or methyldopa should be taken via the oral route if blood pressure is ≥ 150/90 mmHg. For chronic hypertension, other drugs should be added after the first drug at the highest concentration has been revealed to be ineffective. If the blood pressure of patients with acute hypertension is ≥ 160/110 mmHg, maternal stroke or eclampsia can result. If PIH patients are about to deliver, they can be given labetalol (i.v.), hydralazine (i.v.) or nifedipine (p.o.). Moreover, all anti-hypertensive treatments should be based on considerations of maternal and fetal safety.

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IJERPH, Free Full-Text

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Lesson: Review of Hypertension in Pregnancy for Pharmacists

Lesson: Review of Hypertension in Pregnancy for Pharmacists

HYPERTENSIVE DISEASE IN PREGNANCY

PREGNANCY INDUCED HYPERTENSION

First-line medication choices in treatment of hypertension of pregnancy

Medication for management of pregnancy-induced hypertension Lin Y, Zhang Y, Jiang YN, Song W - Clin Trials Degener Dis

Diagnosis and management of hypertension in pregnancy: summary of updated NICE guidance

MANAGEMENT OF PREGNANCY INDUCED HYPERTENSION